Win the battle

against biofilm

IoPlex® Iodophor Foam Dressing is shown
to manage biofilm in-vitro.

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Slow-release iodine reduces bacteria

IoPlex with I-Plexomer™ is the world’s only foam dressing that allows for regulated and sustained infection management through the slow release of iodine within the wound dressing.

It’s effective for both acute and chronic wounds — and advanced technologies inside IoPlex address biofilm* and bioburden with three primary modes of action.

*based on in vitro testing

Three modes of action target biofilm:

Active exudate
control

Iodine as the
antibacterial agent

I-Plexomer
technology for
controlled release

Pink circle with 90% in the middle

More than 90% of chronic wounds
contain biofilm, which stalls wound healing1.

What is biofilm?

Biofilms are bacterial structures that physically attach to a surface. They have significant tolerance to antibiotics and biocides. Many argue that the existence of biofilm is the single most important cause of delayed wound healing2. Learn more about biofilm

Learn about the science behind Ioplex
Watch how Ioplex gradually releases iodine


Learn about the science behind IoPlex

Watch how IoPlex gradually releases iodine.

How it Works

Uncover the power of iodine inside IoPlex

The IoPlex portfolio provides a variety of sizes designed to fit the wounds you treat every day, including 2″ x 2″ for smaller wounds; 4″ x 5″ and 6″ x 9″ for larger wounds.

Click to explore

How it Works

Uncover the power of iodine inside IoPlex

The IoPlex portfolio provides a variety of sizes designed to fit the wounds you treat every day, including 2″ x 2″ for smaller wounds; 4″ x 5″ and 6″ x 9″ for larger wounds.

Click to explore

IoPlex outperforms Hydrofera Blue and Silver Dressings

Based on in vitro testing

IoPlex demonstrated a 4 log or greater kill against MRSA in 5 min and P. aeruginosa in 30 min

What the experts are saying

“[Controlled-release iodophors] are appropriate agents for aggressively and reliably controlling biofilms and realigning wounds to a positive healing trajectory.”

A review of iodine-based compounds, with a focus on biofilms: results of an expert panel by Randall D. Wolcott, et al, Journal of Wound Care, July 2020

What the experts are saying

“[Controlled-release iodophors] are appropriate agents for aggressively and reliably controlling biofilms and realigning wounds to a positive healing trajectory.”

A review of iodine-based compounds, with a focus on biofilms: results of an expert panel by Randall D. Wolcott, et al, Journal of Wound Care, July 2020

Manage biofilm with IoPlex*

Request your free sample

Simply complete this form and a Medline Skin Health Representative will contact you to schedule your demo with free sample.

For more information about IoPlex and ordering products, shop our catalog

Why are these products an effective strategy for managing biofilm?*

Experts say, a multi-faceted approach to biofilm helps break the chronic wound cycle. Advanced wound care products like PluroGel Burn and Wound Dressing and IoPlex Iodophor Foam Dressing are an effective strategy against biofilm,* helping patients to wound closure.

*based on in vitro data. Data on file.

Make skin health second nature

References:

  1.  Attinger C and Wolcott R. Clinically addressing biofilm in chronic wounds. Advances in Wound Care. 2012;1(3):127-132. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839004/. Accessed September 16, 2019.
  2. Schultz G, Bjarnsholt T, James GA, Leaper DJ, McBain AJ, Malone M, et al. Consensus guidelines for the identification and treatment of biofilms in chronic nonhealing wounds. Wound Repair and Regeneration.2017;25(5):744-757. Available at: https://onlinelibrary.wiley.com/doi/pdf/10.1111/wrr.12590. Accessed September 16, 2019.
  3. Phillips PL, Yang Q, Sampson E, Schultz G. Effects of antimicrobial agents on an in vitro biofilm model of skin wounds. Advances in Wound Care. 2010; 1:299-304.
  4. Hill KE, Malic S, McKee R, Rennison T, Harding KG, et al. An in vitro model of chronic wound biofilms to test wound dressings and assess            antimicrobial susceptibilities. Journal of Antimicrobial Chemotherapy. 2010; 65(6):195-206.
  5. Thorn RMS, Austin AJ, Greenman J, Wilkins JPG, Davis PJ. In vitro comparison of antimicrobial activity of iodine and silver dressings against     biofilms. Journal of Wound Care. 2009;18(8):343-346.
  6. Phillips PL, Yang Q, Davis S, Sampson EM, Azeke JI, et al. Antimicrobial dressing efficacy against mature Pseudomonas aeruginosa biofilm on porcine skin explants. International Wound Journal. 2015; 12(4):469-483.
  7. Data on file.
  8. Wolcott RD, Hanson JD, Rees EJ, Koenig LD, Phillips CD, Wolcott RA, Cox SB, White JS. Analysis of the chronic wound microbiota of 2,963     patients by 16S rDNA pyrosequencing, Wolcott, R.D. et al Wound Rep Reg (2016) 24 163–174