Hyalomatrix Hyaluronic Acid Wound Device
 
 

Hyalomatrix Hyaluronic Acid Wound Device

Manufacturer: Medline
  • Sterile, flexible wound device with two layers: a semipermeable silicone membrane, and a nonwoven pad made of HYAFF, an esterified hyaluronic acid (HA)
  • Biodegradable matrix acts as a scaffold for cellular colonization (e.g. fibroblasts) and capillary growth, facilitating ordered reconstruction of dermal tissue
  • Removal of the silicone layer of Hyalomatrix is recommended when the tissue underneath is healed, or ready for grafting, typically 14 to 21 days after application
  • Can help facilitate the healing process in slow-healing and chronic wounds, including partial and full-thickness wounds; second-degree burns; pressure injuries, venous, diabetic or chronic vascular ulcers; tunneled/ undetermined wounds; some surgical and trauma wounds; and draining wounds

For your business

To view pricing and availability

 

Ordering Information

 
 
Material Description Packaging
MSS4011 Hyalomatrix Wound Device, 2.5 cm x 2.5 cm 10/BX
Stock Allocated QTY / Remaining QTY / Allocation Reset Date
MSS4011H Hyalomatrix Wound Device, 2.5 cm x 2.5 cm 1 EA
Stock Allocated QTY / Remaining QTY / Allocation Reset Date
MSS4011NS Hyalomatrix Nonsilicone Wound Device, 2.5 cm x 2.5 cm 10/BX
Stock Allocated QTY / Remaining QTY / Allocation Reset Date
MSS4011NSH Hyalomatrix Wound Device, 2.5 cm x 2.5 cm, Nonsilicone 1 EA
Stock Allocated QTY / Remaining QTY / Allocation Reset Date
MSS4022 Hyalomatrix Wound Device, 5 cm x 5 cm 10/BX
Stock Allocated QTY / Remaining QTY / Allocation Reset Date
MSS4022H Hyalomatrix Wound Device, 5 cm x 5 cm 1 EA
Stock Allocated QTY / Remaining QTY / Allocation Reset Date
MSS4022NS Hyalomatrix Nonsilicone Wound Device, 5 cm x 5 cm 10/BX
Stock Allocated QTY / Remaining QTY / Allocation Reset Date
MSS4022NSH Hyalomatrix Wound Device, 5 cm x 5 cm, Nonsilicone 1 EA
Stock Allocated QTY / Remaining QTY / Allocation Reset Date
MSS4044 Hyalomatrix Wound Device, 10 cm x 10 cm 1 EA
Stock Allocated QTY / Remaining QTY / Allocation Reset Date
MSS4044NS Hyalomatrix Nonsilicone Wound Device, 10 cm x 10 cm 1 EA
Stock Allocated QTY / Remaining QTY / Allocation Reset Date
MSS4048 Hyalomatrix Wound Device, 10 cm x 20 cm 1 EA
Stock Allocated QTY / Remaining QTY / Allocation Reset Date
MSS4048NS Hyalomatrix Nonsilicone Wound Device, 10 cm x 20 cm 1 EA
Stock Allocated QTY / Remaining QTY / Allocation Reset Date
MSS4088 Hyalomatrix Wound Device, 18 cm x 20 cm 1 EA
Stock Allocated QTY / Remaining QTY / Allocation Reset Date
MSS4088NS Hyalomatrix Nonsilicone Wound Device, 18 cm x 20 cm 1 EA
Stock Allocated QTY / Remaining QTY / Allocation Reset Date
 

Adhesive
  • No
Antimicrobial
  • No
Area of Application
  • All Over Body
Brand
  • Hyalomatrix
Dressing Change Frequency/Use
  • 14-21 days (Check weekly)
Dressing Pad Size
  • 1" x 1"
  • 2" X 2"
  • 3.9" x 3.9"
  • 3.9" x 7.9"
  • 7.9" x 7.1"
Dressing Type
  • Hyaluronic Acid Wound Device
EP Packaging
  • Yes
Latex Free
  • Yes
Length Centimeters
  • 2.5 cm
  • 5 cm
Length Inches
  • 1 "
  • 2 "
  • 3.9 "
  • 7.9 "
Primary or Secondary Dressing
  • Primary Dressing
Product Category
  • Biologic/Skin Sub
Product Shape
  • Square
  • Rectangle
Product Type
  • Wound Matrix
  • Vascular Graft
Retail Packaging
  • No
Silver
  • No
Sterile
  • Yes
UNSPSC
  • 42295513
Waterproof Outer Layer
  • Yes
  • No
Width Centimeters
  • 2.5 cm
  • 5 cm
Width Inches
  • 1 "
  • 2 "
  • 3.9 "
  • 7.1 "
Wound Condition Type
  • Burn & Wound

Corius tissue regeneration logo

Welcome to Corius

We have one goal: to provide breakthrough technologies for transforming injured skin into healthy skin.

Corius is derived from the Latin word meaning skin. Corius is a division of Medline created to help empower the surgical community to advance quality healing and enable better outcomes for patients. At the heart of our commitment are clinicians, researchers, scientists and entrepreneurs driven to discover unique mechanisms of action designed to optimize the speed and quality of healing.

Learn more about the Corius division

Hyalomatrix

Facilitate closure and help patients get back to their lives quickly.

Using the dermal regeneration properties of hyaluronic acid (HA), Hyalomatrix helps you rebuild tissue. HA is a main component of the extracellular matrix and is considered one of the key players in the tissue regeneration process.1 Hyalomatrix puts HA’s innate tissue regeneration properties in your skilled hands, helping you bring new hope to patients and their families. It features HYAFF, an exceptionally long-lasting form of HA. HYAFF delivers HA to the wound bed in a prolonged manner, facilitating each stage of the healing process.2-6

Gloved hands holding wound dressing

Clinical evidence

Hyalomatrix. Well-established. Well-documented.

The roles of HA, HYAFF and Hyalomatrix are supported by more than 800 peer-reviewed published papers.

750+

Exploratory research studies on hyaluronic acid

45

HYAFF technology studies

34

Hyalomatrix clinical studies

Published evidence

Title Publication Authors Year
1 Esterified Hyaluronic Acid Matrix in Lower Extremity Reconstruction With Exposed Tendon and Bone: A Retrospective Review J Burn Care Res. 2020 Jul 3;41(4):828-834. Kozusko SD, Hassouba M, Hill DM, Liu X, Dadireddy K, Velamuri SR 2020
2 Neodermis formation in full thickness wounds using an esterified hyaluronic acid matrix Journal of Burn Care & Research 2019. Aballay A, Hermans MHE. 2019
3 Preclinical and Clinical Studies of Hyaluronic Acid in Wound Care: A Case Series and Literature Review Wounds 2019 Feb;31(2):41–48. Schneider HP, Landsman 2019
4 Necrotizing Fasciitis: An Overview and 2 Illustrative Cases Wounds 2018 Dec;17(4):295-300 Kapp DL, Rogers M, Hermans MHE 2018
5 Outcomes of an Esterified Hyaluronic Acid Matrix in the Treatment of Chronic Lower Extremity Wounds: A Case Series Wounds 2018 Dec;30(12):367-371 Cheung T, Laidley Z, Jones J, Wu S 2018
6 Use of Hyaluronic Acid–Based Biological Bilaminar Matrix in Wound Bed Preparation: A Case Series ePlasty 2018 Feb 22;18:e10 Simman R, Mari W, Younes S, Wilson M. 2018
7 Venous Ulcers Treated With a Hyaluronic Acid Extracellular Matrix and Compression Therapy: Interim Analysis of a Randomized Controlled Trial Wounds 2017;29(7):E51–E54. Alvarez OM, Makowitz L, Patel M 2017
8 Hyaluronic Acid in Inflammation and Tissue Regeneration Wounds 2016;28(3):78-88. Litwiniuk M, Krejner A, Grzela T. 2016
9 Limb Trauma: the use of an advanced wound care device in the treatment of full-thickness wounds Strat Traum Limb Recon 2013;8:111-115. Vaienti L, Marchesi A, Palitta G, Gazzola R, Parodi PC, Leone F 2013
10 Interaction between a regenerative matrix and wound bed in nonhealing ulcers: results with 16 cases Biomed Res Int 2013; 2013:849321. Motolese A, Vignati F, Brambilla R, Cerati M, Passi A. 2013
11 Wound Bed Preparation with a Dermal Substitute (Hyalomatrix PA) Facilitates Re-epithelialization and Healing: Results of a Multicenter, Prospective, Observational Study on Complex Chronic Ulcers (The FAST Study) Wounds 2011;23(8):228-235. Caravaggi C, Grigoletto F, Scuderi N. 2011
12 Hyaluronan Benzyl Ester as a Scaffold for Tissue Engineering International Journal of Molecular Sciences 2009; 10: 2972-2985. Vindigni V, Cortivo R, Iacobellis L, Abatangelo G, Zavan B. 2009
13 Skin pH Variations from the Acute Phase to Re-Epithelialization in Burn Patients Treated with New Materials (Burnshield, Semipermeable, Adhesive Film, Dermasilk, and Hyalomatrix). Non-invasive preliminary Experimental Clinical Trial Annals of Burns and Fire Disasters 2008; 21(2):73-77. Osti E. 2008

Request additional studies/pediatric studies from Medical Affairs.

References
  1. Litwiniuk M, Krejner A, Speyrer MS, Gauto AR, Grzela T. Hyaluronic Acid in Inflammation and Tissue Regeneration. Wounds. 2016 Mar;28(3):78-88. PMID: 26978861.
  2. Caravaggi C, Grigoletto F, Scuderi N. Wound Bed Preparation With a Dermal Substitute (Hyalomatrix® PA) Facilitates Re-epithelialization and Healing: Results of a Multicenter, Prospective, Observational Study on Complex Chronic Ulcers (The FAST Study). WOUNDS 2011;23(8):228–235. Available at: http://www.medscape.com/viewarticle/749515_1 Accessed June 18, 2018.
  3. Voigt J, Driver VR. Hyaluronic Acid Derivatives and Their Healing Effect on Burns, Epithelial Surgical Wounds, and Chronic Wounds: a Systematic Review and Meta-Analysis of Randomized Controlled Trials. Wound Repair Regen. 2012 May-Jun;20(3):317-31. Available at: http://www.ncbi.nlm.nih.gov/pubmed/22564227 Accessed June 18, 2018.
  4.  Gravante G, Sorge R, Merone A, et al. Hyalomatrix PA in Burn Care Practice: Results From a National Retrospective Survey, 2005–2006. Ann Plast Surg. 2010;64(1):69–79.
  5. Longinotti C. The Use of Hyaluronic Acid-Based Dressings to Treat Burns: A Review. Burn Trauma [Epub ahead of print] [cited 2014 Oct 16]. Available from: http://burnstrauma.com/temp/BurnTrauma24162-6158285_170622.pdf Accessed June 20, 2018.
  6. Moseley R, Walker M, Waddington RJ, Chen WYJ. Comparison of the Antioxidant Properties of Wound Dressing Materials–Carboxymethylcellulose, Hyaluronan Benzyl Ester and Hyaluronan, Towards Polymorphonuclear Leukocyte-Derived Reactive Oxygen Species. Biomaterials (Impact Factor: 8.31). 05/2003; 24(9):1549-57.

  • Hyalomatrix Application

    /catalog/includes/play-video.jsp?url=https://player.vimeo.com/video/150727529
  • https://player.vimeo.com/video/286618278

    /catalog/includes/play-video.jsp?url=https://player.vimeo.com/video/286618278
  • https://player.vimeo.com/video/329192604

    /catalog/includes/play-video.jsp?url=https://player.vimeo.com/video/329192604
  • https://player.vimeo.com/video/349739118

    /catalog/includes/play-video.jsp?url=https://player.vimeo.com/video/349739118
  • https://player.vimeo.com/video/353650258

    /catalog/includes/play-video.jsp?url=https://player.vimeo.com/video/353650258

Literature

SDS

Category Id: - Content Id: