Hyalomatrix Wound Device
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Hyalomatrix Wound Device

  • Bi-layered, sterile, flexible and conformable wound device
  • Non-woven pad comprised entirely of HYAFF®, esterified hyaluronic acid
  • Semipermeable silicone membrane controls water vapor loss, provides a flexible covering for the wound surface, and adds increased tear strength
  • Biodegradable matrix acts as a scaffold for cellular colonization (e.g. fibroblasts) and capillary growth, facilitating ordered reconstruction of dermal tissue
  • Indicated for partial and full-thickness wounds, second-degree burns, pressure injuries, venous ulcers, diabetic ulcers, chronic vascular ulcers, tunneled/undetermined wounds, surgical wounds (donor sites/grafts, post-Mohs surgery, post-laser surgery, podiatric, wound dehiscence), trauma wounds (abrasions, lacerations, skin tears), and draining wounds
  • Removal of the silicone layer of Hyalomatrix is recommended when the tissue underneath is healed, or ready for grafting, typically 14 to 21 days after application
  • To cover Hyalomatrix, a non-adherent secondary dressing should be chosen by wound location, size, depth and user preference

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Ordering Information

Material Description Packaging
MSS4011 Wound Device: Hyalomatrix Wound Device, 2.5 x 2.5 cm 10/BX
MSS4011H Wound Device: Hyalomatrix Wound Device, 2.5 x 2.5 cm 1 EA
MSS4022 Wound Device: Hyalomatrix Wound Device, 5 x 5 cm 10/BX
MSS4022H Wound Device: Hyalomatrix Wound Device, 5 x 5 cm 1 EA
MSS4044 Wound Device: Hyalomatrix Wound Device, 10 x 10 cm 1 EA
MSS4048 Wound Device: Hyalomatrix Wound Device, 10 x 20 cm 1 EA


Adhesive No
Antimicrobial No
Area of Application All Over Body
Brand Hyalomatrix
Diameter Inches 1", 6.25", 16", 32"
Dressing Type Sheet
EP Packaging Yes
HPIS Code 740_80_0_0
Latex Free Yes
Length Centimeters 2.5 cm, 5 cm
Length Inches 1 ", 2.5 ", 3.9", 7.9"
Material 100% Hyaff, Esterified HA
Package Type 10ea/bx, 1 Each
Product Category Hyaluronic Acid Wound Device
Product Shape Square, Rectangle
Product Type Wound Matrix
Retail Packaging No
Silver No
Sterile Yes
UNSPSC 42295513
Waterproof Outer Layer Yes
Width Centimeters 2.5 cm, 5 cm
Width Inches 1 ", 2.5 ", 3.9"
Wound Condition Type Burn & Wound

More about this item

Biologically derived reconstructive matrix

Hyalomatrix is a sterile, flexible wound device consisting of two layers: a non-woven pad of HYAFF, esterified hyaluronic acid (HA), and a semi-permeable silicone membrane.

A unique hyaluronic acid-based wound care technology, Hyalomatrix’s HYAFF fibers help facilitate the healing process in slow-healing and chronic wounds, including venous ulcers, diabetic foot ulcers, pressure ulcers, as well as second degree burns and surgical sites (1,2,3,4,5). The thin, semi-permeable silicone layer protects the wound from external contamination, controls moisture loss, and increases tear strength.


Available in Four Sizes.

  • 1″ x 1″ (2.5 cm x 2.5 cm)
  • 2″ x 2″ in (5×5 cm)
  • 3.9″ x 3.9″ in (10 x 10cm)
  • 3.9″ x 7.9″ in (10 x 20cm)


1. Caravaggi C, Grigoletto F, Scuderi N. Wound Bed Preparation With a Dermal Substitute (Hyalomatrix® PA) Facilitates Re-epithelialization and Healing: Results of a Multicenter, Prospective, Observational Study on Complex Chronic Ulcers (The FAST Study). WOUNDS 2011;23(8):228–235. Available at: www.medscape.com/viewarticle/749515_1 Accessed on Oct 13, 2014.
2. Gravante G, Sorge R, Merone A, et al. Hyalomatrix PA in Burn Care Practice: Results From a National Retrospective Survey, 2005–2006. Ann Plast Surg. 2010;64(1):69–79.
3. Voigt J, Driver VR. Hyaluronic Acid Derivatives and Their Healing Effect on Burns, Epithelial Surgical Wounds, and Chronic Wounds: a Systematic Review and Meta-Analysis of Randomized Controlled Trials. Wound Repair Regen. 2012 May-Jun;20(3):317-31. Available at: www.ncbi.nlm.nih.gov/pubmed/22564227 Accessed Oct 14, 2014.
4. Longinotti C. The Use of Hyaluronic Acid-Based Dressings to Treat Burns: A Review. Burn Trauma [Epub ahead of print] [cited 2014 Oct 16]. Available from: www.burnstrauma.com/preprintarticle.asp?id=142398 Accessed Oct 16, 2014.
5. Moseley R, Walker M, Waddington RJ, Chen WYJ. Comparison of the Antioxidant Properties of Wound Dressing Materials–Carboxymethylcellulose, Hyaluronan Benzyl Ester and Hyaluronan, Towards Polymorphonuclear Leukocyte-Derived Reactive Oxygen Species. Biomaterials (Impact Factor: 8.31). 05/2003; 24(9):1549-57.


  • Hyalomatrix Application

  • https://player.vimeo.com/video/353650258

  • https://vimeo.com/141535447





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