Clinical Resources

Key References

  • Open Abdomen in Trauma and Critical Care Learn More
  • Intensive Monitoring of Urine Output is Associated with Increased Detection of Acute Kidney Injury and Improved Outcomes Learn More
  • Inaccuracy of Urine Output Measurements due to Urinary Retention in Catheterized Patients in the Burn ICU Learn More
  • Kato R, Pinsky MR. Personalizing Blood Pressure Management in Septic Shock. Annals of Intensive Care. 2015;5:41.
  • Automated, accurate urine output and intra-abdominal pressure monitoring can be used to personalize blood pressure management for critically ill patients to avoid damage to organs from over or under
    resuscitation. Learn More
  • Henry KE, Hager DN, Pronovost PJ, Saria S. A Targeted Real-time Early Warning Score (TREWScore) for Septic Shock. Science Translational Medicine. 2015;7(299):299ra122.
  • Sepsis study on 13,014 patients showed that urine output was more useful than SIRS criteria themselves. Learn More

Additional References

  • Fact Sheet SEP-1: Early Management Bundle, Severe Sepsis/Septic Shock. Center for Medicare and Medicaid Services. October 2015
  • Martin GS. Sepsis, Severe Sepsis and Septic Shock: Changes in Incidence, Pathogens and Outcomes. Expert Review of Anti-infective Therapy. 2012;10(6):701-706
  • Shorr AF, Micek ST, Jackson WL Jr., Kollef MH. Economic Implications of an Evidence-based Sepsis Protocol: Can We Improve Outcomes and Lower Costs? Crit Care Med. 2007;35(5):1257-1262
  • Kumar G, Kumar N, Taneja A, et al. Nationwide Trends of Severe  Sepsis in the 21st Century (2000-2007). Chest. 2011; 140(5):1223-1231
  • Shaefi S, O’Gara B, Kociol RD, et al. Effect of Cardiogenic Shock Hospital Volume on Mortality in Patients With Cardiogenic Shock. J Am Heart Assoc. 2015;4(1):e001462
  • Vaara ST, Korhonen A-M, Kaukonen K-M, et al. Fluid Overload Is Associated With an Increased Risk for 90-Day Mortality in Critically Ill Patients With Renal Replacement Therapy: Data From the Prospective FINNAKI Study. Critical Care. 2012;16(5):R19
  • Critical Care Statistics. Society of Critical Care website. Available at:
  • Leite TT, Macedo E, Pereira SM, et al. Timing of Renal Replacement Therapy Initiation by AKIN Classification System. Critical Care. 2013;17(2):R62
  • Mandelbaum T, Scott DJ, Lee J, et al. Outcome of Critically Ill Patients With Acute Kidney Injury Using the AKIN Criteria. Critical Care Medicine. 2011;39(12):2659-2664
  • Magee G, Zbrozek A. Fluid Overload Is Associated With Increases in Length of Stay and Hospital Costs: Pooled Analysis of Data From More Than 600 US Hospitals. ClinicoEconomics and Outcomes Research: CEOR. 2013;5:289-296
  • Dellinger R, Levy M, Rhodes A, et al. Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012. Critical Care Medicine. 2013;41(2):580-637
  • Pinsky MR. Functional Hemodynamic Monitoring. Critical Care Clinics. 2015;31(1):89-111
  • Grossini E, Molinari C, Pollesello P, et al. Levosimendan Protection Against Kidney Ischemia/Reperfusion Injuries in Anesthetized Pigs. Journal of Pharmacology and Experimental Therapeutics. 2012;342(2):376-388
  • Shamir MY, Kaplan L, Marans RS, et al. Urine Flow Is a Novel Hemodynamic Monitoring Tool for the Detection of Hypovolemia. Anesth Analg. 2011;112(3):593-596
  • Khosravi MB, Jalaeian H, Lahsaee M, et al. The Effect of Clamping of Inferior Vena Cava and Portal Vein on Urine Output During Liver Transplantation. Transplant Proc. 2007;39(4):1197-1198
  • Cheatham ML. Intraabdominal Pressure Monitoring During Fluid Resuscitation. 2008;14(3):327-333
  • Connor M. Presentation on Abdominal Compartment Syndrome, Critical Care Nephrology: 2015 Update. American Society of Nephrology.
  • Danek G, Gravenstein N, Lizdas DE, Lampotang S. Prevalence of Dependent Loops in Urine Drainage Systems in Hospitalized Patients. J Wound Ostomy Continence Nurs. 2015;42(3):273-278
  • Garcia M, et al. Traditional Foley Drainage Systems–Do They Drain the Bladder? J Urol. 2007;177(1):203-207
  • Drewry AM, Fuller BM, Bailey TC, Hotchkiss RS. Body Temperature Patterns as a Predictor of Hospital-Acquired Sepsis in Afebrile Adult Intensive Care Unit Patients: A Case-Control Study. Critical Care. 2013;17(5):R200
  • Drvar Ž, Mirić M, Pavlek M, et al. Correlation Between Intraabdominal Hypertension and Arterial Lactate Concentration in Severe Sepsis Patients. Signa Vitae. 2014;9(Suppl 1):25-28
  • Malbrain MLNG, Chiumello D, Pelosi P, et al. Prevalence of Intra-Abdominal Hypertension in Critically Ill Patients: A Multicentre Epidemiological Study. Intensive Care Med. 2004;30(5):822-829
  • Beeckman D, Van Lancker A, Van Hecke A, Verhaeghe S. A Systematic Review and Meta-Analysis of Incontinence-Associated Dermatitis, Incontinence, and Moisture as Risk Factors for Pressure Ulcer Development. Res Nurs Health. 2014;37(3):204-218
  • Hooton TM, Bradley SF, Cardenas DD, et al. Diagnosis, Prevention, and Treatment of Catheter-associated Urinary Tract Infection in Adults: 2009 International Clinical Practice Guidelines From the Infectious Diseases Society Of America. Clin Infect Dis. 2010;50(5)625-663
  • Details for Title: CMS-1607-F and Other Associated Rules and Notices. Centers for Medicare & Medicaid Services website. Available at:
  • Felix K. Guide to the Elimination of Catheter-Associated Urinary Tract Infections. Association For Professionals in Infection Control and Epidemiology website. Available at:

The Accuryn system is a 510(k) cleared device available for sale in the United States.